PRELIMINARY RESULTS OF 1 YEAR TREATMENT WITH BIOSYNTHETIC GROWTH HORMONE IN 7 CASES OF CLASSIC GROWTH HORMONE DEFICIENCY
Keywords:Growth hormone deficiency; biosynthetic growth hormone; height velocity.
AbstractSeven cases of classic growth hormone deficiency who were previously untreated, were treated with biosynthetic growth hormone. Their mean chronological age was 10.67 ± 2.93, with height age o 5.51 ± 3.53, bone age of 6.14 ± 3.86 and with bone age lag of 48.85 %. Mean pretreatment height velocity of these cases was 2.97 ± 0.93 cm/year. Biosynthetic hGH (Norditropin and Genotropin) was administrated in a dose of 12 units/m /Week at night time. After 1 year their mean height velocity had increased to 8.46 ± 2.71 cm/year. Maximum increase in height was seen during second trimester of therapy.
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