Does nitric oxide inhalation need to be reassessed?


  • Khalid A Dahiyat



Nitric Oxide. Respiratory Distress Syndrome, Newborn. Endothelium-Dependent Relaxing Factors. Persistent Fetal Circulation Syndrome. Bronchopulmonary Dysplasia. Pharmaceutical Preparations. Bronchodilator Agents. Administration, Inhalation. Cyclic


Background: Inhaled nitric oxide is a drug which has been given FDA approval in 1999 but was not found prior to approval to be safe for use in premature neonates. Aim: To review and assess the studies which was done prior to its approval in order to find out what evidences the approval by the FDA was based on. Methods: A thorough search of the electronic data-base, Medline, Embase, Cinahl, Google. Conclusion: The use of this drug in treatment of the Pulmonary hypertension in premature babies is still contraversial and hold a serious untoward effects on the health, it should only used as the last ditch.



How to Cite

Dahiyat, K. A. (2016). Does nitric oxide inhalation need to be reassessed?. Annals of King Edward Medical University, 12(1).




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