Role Of Cisplatin And Cyclophosphamide Chemotherapy In Bulky Residual Disease After Primary Cytoreductive Surgery Of Epithelial Ovarian Cancers.

SHAHARYAR .; Z  ALAUDDIN; Z  FARUQUI; M  HUSSAIN; N  MANZOOR; Z  RASOOL; A J  HUSSAIN

doi:10.21649/akemu.v4i1.3762

Role Of Cisplatin And Cyclophosphamide Chemotherapy In Bulky Residual Disease After Primary Cytoreductive Surgery Of Epithelial Ovarian Cancers.

Authors

SHAHARYAR .
Z ALAUDDIN
Z FARUQUI
M HUSSAIN
N MANZOOR
Z RASOOL
A J HUSSAIN

DOI:

https://doi.org/10.21649/akemu.v4i1.3762

Keywords:

Cytoreduction surgery, chemotherapy, and ovarian tumour.

Abstract

From May 1993 to June 1997, 58 patients with bulky residual disease after primary cytoreductive surgery of epithelial ovarian cancer were treated with cisplatin and cyclophosphamide combination chemotherapy. Overall responses were seen in 30 patients (51.72%) with complete responses in 9 patients (15.51%) and partial responses in 21 patients (36.11%) at 4 months. 28 patients (48.27%) were non-responders. Response in relation to the size of residual disease revealed that 24 out of 36 patients (66.66%) did not show a complete response to chemotherapy. It is concluded that bulky residual disease of greater than 4 cm responds poorly to cisplatin and cyclophosphamide combination chemotherapy.

Downloads

Published

08/11/2020

How to Cite

., S., ALAUDDIN, Z. ., FARUQUI, Z. ., HUSSAIN, M. ., MANZOOR, N. ., RASOOL, Z. ., & HUSSAIN, A. J. . (2020). Role Of Cisplatin And Cyclophosphamide Chemotherapy In Bulky Residual Disease After Primary Cytoreductive Surgery Of Epithelial Ovarian Cancers. Annals of King Edward Medical University, 4(1), 13–15. https://doi.org/10.21649/akemu.v4i1.3762

Download Citation

Issue

Vol. 4 No. 1 (1998): AKEMU

Section

Research Articles

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments publications@kemu.edu.pk

Most read articles by the same author(s)

M Z BASHIR, A R MALIK, P A RANA, S A MALIK, M A SHAHEEN, J I KHOKHAR, M KHALID, M HUSSAIN, Firearm Related Deaths in Lahore A Need for Efficient Emergency Services , Annals of King Edward Medical University: Vol. 7 No. 2 (2001): AKEMU
M HUSSAIN, S AKHTAR, M A CHOUDHRY, N DIN , Close Intubation of Lacrimal Drainage System in Children. , Annals of King Edward Medical University: Vol. 4 No. 3 (1998): AKEMU
Nabela Shami, Shaila Anwar, Iram Akmal, Naheed Zafar, Shaheena Asif, Shaharyar ., Vesico vaginal fistula after interval debulking in epithelial ovarian cancer , Annals of King Edward Medical University: Vol. 11 No. 3 (2005): AKEMU
Fatima Asif, Ambreen Sattar, Shaharyar ., Clinicopathologic features of epithelial ovarian cancer , Annals of King Edward Medical University: Vol. 12 No. 1 (2006): AKEMU
S NIAZI, A S CHUGHTAI, N IQBAL, I A NAVEED, M HUSSAIN, H MUSHTAQ, The Role of Fine Needle Aspiration Cytology (FNAC) in the Diagnosis of Thyroid Lesions , Annals of King Edward Medical University: Vol. 6 No. 1 (2000): AKEMU
SHAHARYAR ., N SHAMI, Z ALAUDDIN, A MAHMOOD, I MAHMOOD, M CHAUDHRY, M HUSNAIN, Z RASOOL, M FAROOQ, A J HUSSAIN, S ASIF, Results of Radiotherapy and Concomitant Cisplatin Chemotherapy in Locally Advanced Squamous Cell Carcinoma of Uterine Cervix , Annals of King Edward Medical University: Vol. 6 No. 3 (2000): AKEMU
N Hussain, M Hussain, I A Naveed, The Role of Fine Needle Aspiration Cytology in the Diagnosis of Thyroid Nodule , Annals of King Edward Medical University: Vol. 8 No. 1 (2002): AKEMU
M MOIN, M HUSSAIN, N A AASI, Dacryocystorhinostomy, Collagen Sponge and Intubation , Annals of King Edward Medical University: Vol. 7 No. 3 (2001): AKEMU
M HUSSAIN, M MOIN, N A AASI, Usefulness of Autokeratoplasty , Annals of King Edward Medical University: Vol. 6 No. 4 (2000): AKEMU
F FAHIM, SHAHARYAR ., A MAHMOOD, Clinicopathological Features of Bronchogenic Carcinoma: A Series of 59 Patients , Annals of King Edward Medical University: Vol. 6 No. 1 (2000): AKEMU

> >>

Role Of Cisplatin And Cyclophosphamide Chemotherapy In Bulky Residual Disease After Primary Cytoreductive Surgery Of Epithelial Ovarian Cancers.