SARS-CoV-2: Cytokine Storm and Therapy


  • Mir Ibrahim Sajid
  • Javeria Tariq
  • Shehar Bano Awais
  • Zehra Naseem
  • Samira Shabbir Balouch
  • Sajid Abaidullah


SARS-CoV-2, Cytokine Storm, Cytokines, Chemokines, Therapy, Anti-Viral Therapies, Anti-Inflammatory Therapies, Review


SARS-CoV-2 can vary on a spectrum of an asymptomatic disease process, to a severe stage characterized by a “Cytokine Storm”. This phenomenon is a pro-inflammatory state marked by an intricate interplay of a cocktail of chemokines and cytokines. An excessively raised serum levels of cytokines and chemokines can lead to the development of acute respiratory distress syndrome. This article highlights the pathophysiologic mechanisms responsible for creating this cytokine havoc and delves into potential therapeutic interventions



How to Cite

Sajid, M. I. ., Tariq, J. ., Awais, S. B. ., Naseem, Z. ., Balouch, S. S. ., & Abaidullah, S. . (2020). SARS-CoV-2: Cytokine Storm and Therapy. Annals of King Edward Medical University, 26(Special Issue), 243-251. Retrieved from



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