TY - JOUR AU - Akram, Humaira AU - Khanum, Zohra AU - Nasir, Alia AU - Rana, Tabinda PY - 2016/03/21 Y2 - 2024/03/29 TI - Goserline versus danazol in the treatment of endometriosis JF - Annals of King Edward Medical University JA - Annals KEMU VL - 12 IS - 1 SE - Articles DO - 10.21649/akemu.v12i1.823 UR - https://www.annalskemu.org/journal/index.php/annals/article/view/823 SP - AB - <p>Objective: The objective of this study was to achieve symptoms relief of endometriosis with a drug having better efficacy and least side effects. Study Design: Experimental. Place &amp; Duration of Study: Lady Willingdon Hospital, Lahore from March, 2003 to Feb. 2005. Subjects &amp; Methods: The trial was conducted on two groups; one group (n = 20) received goserline and other group (n=20) received danazol for 6 months. Patients were followed for relief of symptoms including dysmenorrhoea, dyspareunia, lower abdominal pain and menstrual irregularity and appearance of side effects. Results: The results depicted that in Danazol group 50% pain relief was found in 5 patients (25%) while in goserline group in 4 patients (20%). 75% pain relief was seen in 7 patients (35%) in danazol group and 8 patients (40%) in goserline group. 100% of improvement in pain found in equal number of patient that is 8(40%) in both groups. Both drugs were effective in pain relief (P &gt;0.05), Goserline had less side effects as compared to Danazol (P&lt;0.05). Conclusion: Goserline and Danazol are equally effective in symptomatic relief of endometriosis while side effects favoured use of GnRH agonist.</p> ER -