TY - JOUR PY - 2014/05/14 Y2 - 2024/03/29 TI - Frequency of Etiological Factors Leading to Patent Ductus Arteriosus JF - Annals of King Edward Medical University JA - Annals KEMU VL - 19 IS - 1 SE - Articles DO - 10.21649/akemu.v19i1.481 UR - https://www.annalskemu.org/journal/index.php/annals/article/view/481 SP - 45 AB - <p><strong>Abstract</strong><strong><em></em></strong></p> <p>Background:&nbsp;&nbsp;Patent Ductus Arteriosus (PDA) is dev-eloping as major problem in our society. Many studies in Pakistan has been done to analyze the efficacy of surgical procedures but no one tried to find the fre-quency of factors leading to this problem.</p> <p>Objective:&nbsp;&nbsp;The purpose of this study was to find out the frequency of factors leading to patent ductus arte-riosus in children presented at Punjab Institute of Car-diology.</p> <p><strong>Method:&nbsp;&nbsp;</strong>A cross sectional study was conducted on 242 patients of PDA who already have been treated during the year 2006 - 2007. They were interviewed on their regular follow up visits. Their operative infor-mation was gathered from their files.</p><p><strong>Results:</strong> Mean age of children at time of treatment was 6.12 + 5.203 years. Out of 242 children, there were more female (62.8%) as compared to male (37.2%). In this study, 17.8% children inherited the disease from their close relatives and 105 (43.4%) mo-thers had some infectious problems during pregnancy. 103 (42.6%) mothers used antibiotics or other drugs during pregnancy. 11 (4.5%) children had Down synd-rome. One hundred and thirty seven (56.61%) children had premature birth.</p> <p><strong>Conclusion:&nbsp;&nbsp;</strong>Female gender, preterm birth, infection during pregnancy, mother's exposure to drugs and smoking, low birth weight may be etiological factors for development of PDA.</p> <p><strong>Key Words:</strong>&nbsp;&nbsp;Etiological factors, Patent Ductus Arte-riosus, surgical ligation, catheter based procedure.</p> ER -