TY - JOUR AU - Ayesha Basharat, AU - Muhammad Mustafa Qamar, AU - Nyla Basharat, AU - Shehzad Aslam, AU - Akhtar Rasul, AU - Farwa Naqvi, PY - 2019/12/30 Y2 - 2024/03/29 TI - Effect of Garlic, Ginger, and Exercise on Lipid Profile in Healthy Postmenopausal Women JF - Annals of King Edward Medical University JA - Annals KEMU VL - 25 IS - 4 SE - Articles DO - 10.21649/akemu.v25i4.3118 UR - https://www.annalskemu.org/journal/index.php/annals/article/view/3118 SP - AB - <p><strong>Abstract:</strong></p><p><strong>Background: </strong>Coronary artery disease (CAD) is a significant health problem and attains one of the highest susceptibilities among women population.&nbsp; It risks women of every age, but it is more evident after the onset of menopause.</p><p><strong>Objective: </strong>The objective of the study was to assess the effect of garlic, ginger extracts alone and with aerobic exercise on cardiovascular disease (CVD) risk in post-menopausal women.</p><p><strong>Methods:</strong> A total of 160 post-menopausal women aged (50-60 years) fulfilling the inclusion criteria were randomly recruited equally into four groups: G=1. Garlic supplement, G=2. Ginger supplement, G3=Ginger +aerobic exercises, G4=Garlic +aerobic exercise group. Baseline body mass index (BMI), body fat %, and lipid profile took before and after 16 weeks. The Ginger group used ginger extract 1000 mg/day and garlic group used 900mg/day; G3 used the same amount of garlic with aerobic exercise, Group 4 used the same amount of ginger with aerobic exercise. Combined groups performed aerobic exercises at 50-60% heart rate intensity, 30min/days for five times/week.</p><p><strong>Results:</strong> Body weight, body mass index and body fat %, level of cholesterol, low-density lipoprotein, and triglyceride significantly reduced in the combination therapy of garlic and exercise versus any single treatment group (p&lt;0.05). Moreover, the garlic demonstrated superior effects vs. ginger alone (p&lt;0.05).&nbsp;</p><p><strong>Conclusion:</strong> It was concluded that 16 weeks of combination therapy of garlic and exercise were found useful in CVD prevention. However, ginger alone failed to demonstrate any significant effects.</p> ER -