TY - JOUR AU - Memon, Jan Muhammad AU - Athar, M. Amin AU - Akhund, Anwar Ali PY - 2010/03/05 Y2 - 2024/03/28 TI - Clinical Pattern of Urinary Stone Disease in Our Setting JF - Annals of King Edward Medical University JA - Annals KEMU VL - 15 IS - 1 SE - Articles DO - 10.21649/akemu.v15i1.25 UR - https://www.annalskemu.org/journal/index.php/annals/article/view/25 SP - 17 AB - <strong>Objectives: </strong>To study the basic clinical pattern of urinary stone disease in our setting.<br /><strong>Study design: </strong>Descriptive study.<br /><strong>Setting: </strong>Department of surgery of Nawabshah Medical College Nawabshah over a period of 4 years between August 2003<br />to August 2007.<br /><strong>Subjects: </strong>A total of 257 urolith patients with different stone burden enrolled in the study.<br /><strong>Methodology:</strong> Structured and standardized history and clinical investigations collected in all of urolith patients. The<br />diagnosis of stone disease was based on history, physical examination followed by KUB x-ray, ultrasonography and IVU .All<br />patients subjected to open stone surgery. The data were analyzed prospectively with outcome measures of gender, stone<br />location, clinical presentation and operative procedures.<br /><strong>Results:</strong> Out of 257 patients 181 (70.42%) were male and 76 (29.56%) female with male to female ratio of 2.3:1.The age<br />ranged from 1 year to 80 with the mean of 25.8 years. The peak incidence of upper urinary tract stones was in 20-30 years<br />while lower urinary tract stones in both sexes were under 10 years (Table 1). Anatomical distribution of stone showed 116<br />(45.16%) renal, 21 (8.17%) ureteric, 108 (42%) bladder and 12 (4.66%) urethral calculi (Table 2). The commonest clinical<br />presentation was that of pain in 67.31% of patients associated with haematuria in 26.7% of cases. Clinical urinary tract<br />infection (UTI) was in 15% and 8.9% of patients had spontaneous stone passage (lithuria). The symptoms of bladder outlet<br />obstruction (BOO) including retention of urine were in 7% of cases. Calculus anuria was in 1.9% of cases and 8.1% patients<br />had asymptomatic stones. Bilithiasis (chole-nephrolithiasis) was in 5% of cases (Table 3). Open stone surgery included 84<br />(32.68%) simple pylolithotomies, 15 (5.83%) extended pylolithotomies, 6 (2.33%) pylolithotomy and pyloplasty, 5 (1.94%)<br />nephrolithotomy, 6 (2.33%) nephrectomies, 21 (8.17%) uretrolithotomy, Cystolithotomy was 113 (43.96%) cystolithotomy, 2<br />(0.77%) urethrolithotomy and meatotomy in 5 (1.94%) of patients.<br /><strong>Conclusion: </strong>Urolithiasis is increasing problem with high frequency of bladder stones and male predominance in our part of<br />Sindh province. Open surgery is still needed to treat the patients where modern and minimally invasive therapeutic modalities<br />are out of reach and non-availability in public sector. Establishment of modern stone clinics in rural setup is the need of<br />today&rsquo;s medical practice.<br /><strong>Keywords: </strong>Urinary calculi, Clinical profile, Open stone surgery. ER -