TY - JOUR PY - 2018/03/26 Y2 - 2024/03/29 TI - Presence of Left Ventricular Diastolic Dysfunction in Patients of Chronic Obstructive Pulmonary Disease JF - Annals of King Edward Medical University JA - Annals KEMU VL - 24 IS - 1 SE - Articles DO - 10.21649/akemu.v24i1.2306 UR - https://www.annalskemu.org/journal/index.php/annals/article/view/2306 SP - 593-597 AB - <p>The relationship between chronic obstructive pulmonary disease (COPD) and cardiovascular&nbsp;diseases strongly exists as diastolic dysfunction is commonly reported in COPD patients.&nbsp;Objective: This study was conducted to determine the presence of left ventricular diastolic dysfunction in&nbsp;patients of COPD.&nbsp;Material and Methods: A cross sectional study was conducted in Mayo Hospital Lahore for one year. A&nbsp;total of 50 confirmed cases of COPD were included in the study. History of smoking was taken and subjects&nbsp;were examined for positive signs for the clinical, ECG, x-ray chest PA view and pulmonary function tests.&nbsp;Additionally, they were subjected to echocardiography and left ventricular diastolic dysfunctions were noted.&nbsp;Results: In our study, mean age of the patients was 60.7±6.2 years and mean FEV1/FVC ratio was&nbsp;56.9±14.3%. Similarly mean ejection fraction of the patients turned out to be 60.6±4.6. The mean peak mitral&nbsp;filling velocity of the patients was 69.8±15.9 cm/s. The mean peak mitral filling rate of the patients was&nbsp;57.2±30.9 cm/s and mean E/A ratio was 1.3±0.3. The mean iso-volumetric relaxation time of the patients&nbsp;was 84.2±14.7 msec. The mean mitral E deceleration time of the patients was 187.4±25.1 msec. The mean&nbsp;atrial flow reversal was 0.28±0.04. There were 14 (28%) patients having left ventricular diastolic dysfunction.&nbsp;Conclusion: COPD patients had left ventricular diastolic dysfunction and it was related to increase in pulmonary&nbsp;artery pressure.</p> ER -