Effect of Production of Multiple Keloids on Health of the Animal

  • Abdul Mannan Babar
  • Abdul Hannan Nagi
Keywords: Cicatrix, Hypertrophic; Keloid; Models, Animal; Rabbit; Transforming Growth Factor beta 1.

Abstract

Keloids are fibrous tumors developed in the process of wound healing. Keloids are found solely in human species, and not in animals. Keloid animal model has been developed by the authors. Now authors want to investigate if multiple keloids can be produced in one animal without causing any untoward effects on the health of that animal. Objective | To find out effect of production of multiple keloids on health of the animal. Methodology| The study was Quasi-experimental trial and settings were Experimental Research/Pathology Laboratories, University of Health Sciences, Lahore. The duration was 12 months. Two rabbits were taken; one as control, and other as interventional. In interventional rabbit eight keloids were produced, four on each ear, using Mannan & Hannan technique. Results | Eight keloids were produced in one animal without causing any untoward effects on the health of that animal. Conclusion| Multiple keloids can be produced in one animal without causing any untoward effects on the health of that animal.
Published
2018-10-12
Section
Articles