The Study of FEV , FVC and FEV /FVC in Type 1 Diabetes Mellitus and their 11 Correlation with Duration of Type 1 Diabetes Mellitus

Abstract

Objectives: To determine the pulmonary functions of patients with type 1diabetes mellitus. To correlate the pulmonary functions with duration of type 1 diabetes mellitus. Material and Methods: This Cross sectional study was conducted at department of medicine, Mayo hospital Lahore during the months of January to June, 2015. Sixty two patients fulfilling the criteria enrolled through non-probability purposive sampling technique. Informed consent taken anddemographic details noted. Pulmonary functions were performed by using a spirometer. Pulmonary functions include FEV , FVC and FEV / FVC ratio were calculated. Data entered and analyzed through 1 1 SPSS version 17. Mean and standard deviation were calculated for age, height, weight, BMI, duration ofdiabetes and FEV /FVC ratio. The correlation between duration of diabetes and FEV /FVC ratio was 1 1 measured by Pearson coefficient. P value < 0.05 was considered as significant.Results: In this study, mean age of the patients was 28.27±6.07 years, male to female ratio was 1.2:1, mean duration of disease in patients was 9.35±3.05 years and mean value of FEV /FVC ratio of the patients was 1 86.39±31.19. In this study there was negative correlation between duration of disease and FEV /FVC ratio 1of the patients with disease duration less than 10 years i.e. r=-0.048.Conclusion: Our study concluded that no significant correlation between the pulmonary functions and the duration of type 1 diabetes mellitus but positive correlation in patients with disease duration >10 years.