COMPARISON BETWEEN NIFEDIPINE AND RITODRINE AS AN EFFECTIVE TOCOLYTIC AGENT FOR PRETERM LABOUR

  • Nadeem Shahzad
  • Faiqa Saleem
  • Muhammad Shahid
  • Aisha Malik

Abstract

Abstract Background:  Preterm labour is not uncommon and its incidence is 10% of all the pregnancies. It can be a cause of maternal and fetal morbidity and mortality. Of many available tocolytic agents, ritodrine is fre-quently used but it can leads to maternal and fetal complications which include tachycardia or hypertens-ion. Nifedipine is considered to avoid from these com-plications. However, its efficacy is still under debates. Objectives:  The objective of the study was to com-pare the efficacy of nifedipine with ritodrine in tocoly-sis of preterm labor. Study Design:  It was a randomized controlled trial. Place and Duration of Study:  This study was condu- Shahzad N.1 Assistant Professor Department of Obstetrics & Gynaecology, KEMU / Lady Willingdon Hospital, Lahore Saleem F.2 Assistant Professor Department of Obstetrics & Gynaecology, KEMU / Lady Willingdon Hospital, Lahore Shahid M.3 Associate Professor Dept of Paediatrics SIMS / Services Hospital, Lahore Malik A.4 Professor of Obstetrics & Gynaecology KEMU / Lady Willingdon Hospital, Lahore cted at unit 111 Lady Willingdon Hospital Lahore and duration was one year from 1.1.2014 to 31.12.2014. Methodology:  One hundred and twenty patients were randomly divided in two equal groups. Group A pati-ents were given nifedipine and in group B received ri-todrine for prolongation of labor. The two groups were compared with each other for efficacy. Data was colle-cted on a specially designed Performa. Results:  The efficacy of nifedipine was 71.1% and ritodrine was 31.1%. The results were statically signi-ficant (p-value < 0.05). Conclusions:  Nifedipine was proved to be more effe-ctive than ritodrine and the results were statistically significant Key Words:  Preterm labor; ritodrine; nifedipine; pro-longation of labor.
How to Cite
SHAHZAD, Nadeem et al. COMPARISON BETWEEN NIFEDIPINE AND RITODRINE AS AN EFFECTIVE TOCOLYTIC AGENT FOR PRETERM LABOUR. Annals of King Edward Medical University, [S.l.], v. 21, n. 2, p. 113, aug. 2015. ISSN 2079-0694. Available at: <http://www.annalskemu.org/journal/index.php/annals/article/view/708>. Date accessed: 17 jan. 2018. doi: https://doi.org/10.21649/akemu.v21i2.708.
Section
Medicine & Allied