Presence of Left Ventricular Diastolic Dysfunction in Patients of Chronic Obstructive Pulmonary Disease

  • Kaleem Ullah
  • Zafar Niaz
  • Sami Ullah Mumtaz
  • Sajid Abaidullah

Abstract

The relationship between chronic obstructive pulmonary disease (COPD) and cardiovascular diseases strongly exists as diastolic dysfunction is commonly reported in COPD patients. Objective: This study was conducted to determine the presence of left ventricular diastolic dysfunction in patients of COPD. Material and Methods: A cross sectional study was conducted in Mayo Hospital Lahore for one year. A total of 50 confirmed cases of COPD were included in the study. History of smoking was taken and subjects were examined for positive signs for the clinical, ECG, x-ray chest PA view and pulmonary function tests. Additionally, they were subjected to echocardiography and left ventricular diastolic dysfunctions were noted. Results: In our study, mean age of the patients was 60.7±6.2 years and mean FEV1/FVC ratio was 56.9±14.3%. Similarly mean ejection fraction of the patients turned out to be 60.6±4.6. The mean peak mitral filling velocity of the patients was 69.8±15.9 cm/s. The mean peak mitral filling rate of the patients was 57.2±30.9 cm/s and mean E/A ratio was 1.3±0.3. The mean iso-volumetric relaxation time of the patients was 84.2±14.7 msec. The mean mitral E deceleration time of the patients was 187.4±25.1 msec. The mean atrial flow reversal was 0.28±0.04. There were 14 (28%) patients having left ventricular diastolic dysfunction. Conclusion: COPD patients had left ventricular diastolic dysfunction and it was related to increase in pulmonary artery pressure.
Published
2018-03-26
How to Cite
ULLAH, Kaleem et al. Presence of Left Ventricular Diastolic Dysfunction in Patients of Chronic Obstructive Pulmonary Disease. Annals of King Edward Medical University, [S.l.], v. 24, n. 1, mar. 2018. ISSN 2079-0694. Available at: <http://www.annalskemu.org/journal/index.php/annals/article/view/2306>. Date accessed: 25 apr. 2018.
Section
Articles