Coagulation Abnormalities in Pre-Eclampsia-A Study of 40 Subjects.

Abstract

A study of forty diagnosed cases of Pre-eclampsia (P.E) was carried out in Services hospital, Ganga Ram hospital and Lady Wellingdon hospitals of Lahore. Pre-eclampsia complicates about 10-12% of pregnancies .Some of these patients are at risk of developing coagulopathies such as DIC and HELLP syndrome. In the present study coagulation profile and liver function tests were performed in the pre-eclamptic cases to see whether some tests could be used to predict coagulopathy in such cases. The study showed that prothrombin time, activated partial thromboplastin time and liver function tests were normal in all the cases. The hemoglobin level and platelet count were low while ESR was high in Pre-eclamptic cases when compared with comparable normal control pregnant women .The FDP’s and D-dimers were raised in most of the cases of V.E especially those with severe p re-eclampsia .It was also Concluded that D-dimer test is more sensitive as compared to FDP’s: