The Study of FEV1, FVC and FEV1/FVC in Type 1 Diabetes Mellitus and their Correlation with Duration of Type 1 Diabetes Mellitus
Objectives: To determine the pulmonary functions of patients with type 1diabetes mellitus.To correlate the pulmonary functions with duration of type 1diabetes mellitus.
Material and Methods: This Cross sectional study was conducted at department of medicine, Mayo hospitalLahore during the months of January to June, 2015. Sixty two patients fulfilling the criteria enrolled through non-probability purposive sampling technique. Informed consent taken and demographic detailsnoted. Pulmonary functions were performed by using a spirometer. Pulmonary functionsinclude FEV1, FVC andFEV1/FVC ratio were calculated. Data entered and analyzed through SPSS version 17. Mean and standard deviation were calculated for age, height, weight, BMI, duration of diabetes and FEV1/FVC ratio.The correlation between duration of diabetes and FEV1/FVC ratio was measured by Pearson coefficient. P value< 0.05 was considered as significant.
In this study, mean age of the patients was 28.27±6.07 years, male to female ratio was 1.2:1, mean duration of disease in patients was 9.35±3.05 years and mean value of FEV1/FVC ratio of the patients was 86.39±31.19. In this study there was negative correlation between duration of disease and FEV1/FVC ratio of the patients with disease duration less than 10 years i.e. r=-0.048.
Conclusion: Our study concluded that no significant correlation between the pulmonary functions and the duration of type 1 diabetes mellitus but positive correlation in patients with disease duration >10 years.
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