Efficacy and Safety of Carbon Dioxide Ablative Fractional Resurfacing (CO2-AFR) Device in Moderate to Severe Atrophic Acne Scars

Wajieha Saeed, Zahida Rani, Shazia Aslam


Acne having a prevalence of > 90% in adolescents persisting in adulthood, causes inflammation and scaring. Acne scars cause severe social, psychological and cosmetic problems. There are many remedies available for acne scars with variable results. CO2-AFR laser is a new modality with more effectiveness and low side effect profile.

Objective:  To determine the effectiveness and safety of CO2-AFR device in the treatment of moderate to severe atrophic acne scars.

Study Design:  Interventional study.

Place and Duration of Study:  This study was conducted at Dermatology Department Unit-I, Mayo Hospital Lahore and duration was 1 year, from April 2015 to March 2016.

Material and Methods:  The 30 patients of either sex, having moderate to severe atrophic acne scars were enrolled in the study. Pretreatment assessment of acne scars was done by using Goodman & Baron qualitative scarring grading system. Patients were treated at 4 – 5 weeks interval with maximum 5 sessions. Objective assessment for efficacy and side effects was done at each session. Data was collected on a specially designed proforma and statistical analysis carried out by using SPSS version 17.

Results:  Significant improvement in acne scars was observed. 14 (46.7%) patients showed good efficacy (50 – 75% reduction), 1 (3.3%) patient came out with excellent efficacy (> 75%) and 14 (46.7%) patients showed fair efficacy (25 – 50% reduction in acne scars). 13.3% patients showed few delayed side effects which resolved with treatment.

Conclusion:  CO2-AFR device was proved to be effective and safe in the treatment of moderate to severe atrophic acne scars.


Atrophic acne scars, ablative fractional resurfacing (AFR), CO2 laser, fractional photothermolysis (FP).

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DOI: http://dx.doi.org/10.21649/akemu.v23i1.1507


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(C) Annals of KEMU, King Edward Medical University, Lahore, Pakistan.