Comparison of Nalbuphine and Midazolam on the cardiovascular response to Laryngoscopy and intubation

Naila Asad; Khawar Ali; Mazhar Iqbal; Abdul Qayyum

doi:10.21649/akemu.v11i3.1014

Comparison of Nalbuphine and Midazolam on the cardiovascular response to Laryngoscopy and intubation

Authors

Naila Asad
Khawar Ali
Mazhar Iqbal
Abdul Qayyum

DOI:

https://doi.org/10.21649/akemu.v11i3.1014

Keywords:

Laryngoscopy. Nalbuphine. Midazolam. Intubation. Intubation, Intratracheal. Meptazinol. Fentanyl. Heart Rate. Cardiovascular System.

Abstract

Objective: To compare the effects of nalbuphine and midazolam on cardiovascular response to laryngoscopy and intubation -during induction of anaesthesia. Method: Ninety adult male patients of ASA I or II status were included and divided into three equal g roups. Group I was control in which 3ml of saline was given. Group II received nalbuphine 75 ug/kg and Group III received midazolam 30 ug/kg. The cardiovascular response was evaluated at laryngoscopy and every minute after intubation for three minutes.The results were analysed statistically by ANOVA.p<0.05 was taken significant. Results: A decrease in HR, SBP, DBP, MAP was seen after three minutes in Group II and III but the decrease was more pronounced in Group II.(p<0.05) Conclusion: Premedication with nalbuphine 75gg/kg is more effective than midazolam in blunting the haemodynamic response to laryngoscopy and intubation.

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Published

04/16/2016

How to Cite

Asad, N., Ali, K., Iqbal, M., & Qayyum, A. (2016). Comparison of Nalbuphine and Midazolam on the cardiovascular response to Laryngoscopy and intubation. Annals of King Edward Medical University, 11(3). https://doi.org/10.21649/akemu.v11i3.1014

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Issue

Vol. 11 No. 3 (2005): AKEMU

Section

Research Articles

License

This is an open-access journal and all the published articles / items are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. For comments publications@kemu.edu.pk

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Comparison of Nalbuphine and Midazolam on the cardiovascular response to Laryngoscopy and intubation